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Neurotrophins, like nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF), play important roles in neuronal development, function, and survival during early stages of both the central and peripheral nervous system (Machaalani et al., 2019)

On the whole, the pharmaceutical industry not only looked the other way when it came to smoking, but at least one company, Merck Sharp and Dohme, encouraged it by sending personally embossed matchbooks to physicians with ads for its new antihypertensive medications, DIURIL (chlorothizaide) and HYDRODIURIL (hydrochlorothiazide)

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One study found that women who smoke are more than twice as likely as nonsmoking women to have a heart attack